Biology 3316A/B Lecture Notes - Lecture 2: Antigen, Xiap, Oncogene
7 Mar 2018
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Ire1 recruits protein called traf2, which recruits ask1: ask 1 recruits phosphorylated jnk, phosphorylated jnk goes and promotes increase of pro- apoptotic proteins (ex. Apaf-1: which then causes activation of caspase 2 cleaves bid into tbid and so on. Slide 6: mitochondrial stress: mitochondria release multiple pro-apoptotic molecules, such as. Light chain (mlc: this will cause increase of contraction and other factors that will cause the cytoskeleton of cell to detach from cell membrane, causing blebbing to occur. Slide 8: controlled cell death overview: look over slide 8 on powerpoint, dna damage usually causes activation of p53, which will activate. In vertebrates the survival of motor neurons depends on the size of the muscle target field they innervate. If added extra limb to one side, we went from 100 percent neuron generation to 75 percent neuron survival. If an organism"s cells are able to avoid cell death, we will get accumulation of dead cells which are dangerous for organism.
