Biology 3316A/B Lecture Notes - Lecture 2: Aurora Kinase, Repressor, Brain-Derived Neurotrophic Factor
7 Mar 2018
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So these reservoir granules can regulate whether mrna translation and protein synthesis will be activated or degradation of mrna: micrornas also re involved in regulating of mrna translation efficiency and degradation of mrna. A proposed model protein synthesis in cerebellar long-term depression (ltd) If a synapse were allowed to continuously strengthen then the maximum efficiency would be reached and would inhibit encoding of new information, therefore affecting memory. Slide 15: predicted functional synergy of dendritically synthesized proteins. Molecules to make note of: these are dendritic mrnas: b-actin actin dynamics and spine size. Axons, like dendrites, are signal receiving compartments: growing axons require extrinsic signals such as, to regulate their growth, to navigate, to form synapse, to maintain and repair itself. Bdnf are located, these factors will cause translation of the beta actin mrna when it arrives: this can lead to actin polymerization/cytoskeletal assembly and causing attractive turning of the growth cone, will get filopodial extension and attractive turning.
