Biology 3444F/G Lecture Notes - Lecture 3: Allele Frequency, Haplotype, Genetic Drift
17 Apr 2014
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Lecture 3 bio 3444f. More variable markers have more information at close scales. If you want to distinguish things that are very different, want to use a low variability marker. Nuclear generate diploid genotypes. Determining breeding success of males in a small isolated population of grizzly bears - . Microsatellites (highly variable, specifically would want to look at the y- chromosome) Determining whether an invasive weed is an introduction of a european or african subspecies. Mitochondrial dna, sequence variation to generate a haplotype. Heritability is an important factor in natural selection. Hardy- weinberg equilibrium: predicts frequencies of genotypes in a population, given allele frequencies assuming: No factors acting that could change allele frequencies (no selection, no mutation, no genetic drift, no gene flow) equilibrium. Wahlund effect: isolated populations that don"t breed combined together, giving deviation from hardy- weinberg. Allelic diversity = mean # of alleles per locus. Most genetic loci in most organisms are found to be in hardy- weinberg.
