Geography 3431A/B Lecture Notes - Lecture 2: Environmental Health, Toxicant, Observational Study
17 Mar 2020
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Document Summary
Information needs in epidemiology: detecting the health effects of environmental. Understanding of the effects of newly synthesized chemicals on human health hasn"t kept pace with our technological capability. There are 3 classes of potential health effects associated with chemical exposure: acute toxicity or immediate injury from short-term exposure to high doses- burns, reversible injury from repeated or chronic exposure transient liver. Irreversible injury from chronic or repeated exposure cancer, birth defects. Study of distribution, dynamics and determinants of disease in populations. Most powerful study design for establishing evidence of causation for human illness is the rct: neither ethical or feasible to randomize persons to undergo an exposure. Nature and extent of the exposure must be documented exposed and control population must be precisely defined: 2. Health effects must be assessed as unequivocally as possible health effect must validly indicate the presence or risk of a serious health outcome: 3. Alternative explanations for the association must be controlled for: 4.
