Health Sciences 2300A/B Lecture Notes - Lecture 3: Melanoma, Pigment, Yolk

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Lecture 3: the integumentary system. The skin = cutaneous membrane. The top layer above dermis. Made of stratified squamous epithelium. Thinnest layer: stratum corneum: the outmost layer, dead keratinocytes with a layer of protein around them (they have undergone keratinization now called corneocytes). You will sluff off a lot overtime. Callus = abnormal thickening: stratum lucidum: dead keratinocytes (keratinocytes have died but have not finished the keratinization). The bottom layer below the dermis. Made by areolar (packing) and adipose (fat) tissue. The middle layer below epidermis. Strong dense connective tissue (collagen and elastic fibers). Superficial potion (1/5) consists of dense irregular connective tissue with thin collagen fibers. Spider like budles of keratinocytes, arm like processes of langerhans cells and melanocytes: stratum basale: Cuboidal/ columnar keratinocytes, melanocytes and merkel cells. Spaces between fibers contain adipose tissue (fat), hair, nerves, sebaceous glands and sudoriferious glands.

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