Kinesiology 1080A/B Lecture Notes - Amputation, Thalidomide, Primary Motor Cortex

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M1 is not plastic plasticity; where things can change. Contemporary; shown not to be the case. Traditional view; m1 is wired and will stay in that figuration no matter what: dysmelia incomplete development how m1 different - when brain is active. Panel b - left limb is dysmelic . Person with amputation; before and after white (post), black, (pre) What happens to m1 rep, after kindling: mapped out neurons, pre/ control , post/ kindling. As a result of epilepsy the motor map has changed significantly. Penfield"s maps may not match to a person with epilepsy. Another limb has taken over, reorganizing to have more cortical region. Amputation patients best for seeing reorganization of motor cortex. Penfield got orientation for the face to the hand wrong, needs to be flipped 180 degrees. Mirror neuron system - unique system that allows one to observe and learn actions based on other actions; learning through observation.

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