Kinesiology 3480A/B Lecture 5: 5 The Nervous System Continued

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Little sterilized strips with letters or numbers placed on different areas of the brain - how surgeon keeps track of different parts of the brain. Have to map it out before they remove an area of the brain. Historical view is somewhat, but not entirely correct. Thaliodomide- drug used to treat morning sickness for pregnant woman- had a teratogenic effect. Population can tell us how m1 is organized in people who have incomplete limb development- plasticity. Control vs. dysmelic (right)- brain from person in last picture from above. Mapped out the extent of m1 devoted to hand representation- how much area on m1 is devoted to hand. Control- mapped out distance between neurons active when wiggling thumb and pinky finger- expansive area of m1 dedicated to hand representation (cortiomagnification) They do not have as much m1 cortex devoted to the hand. Elegant demonstration of m1 plasticity- decreased amount of cortex for hand.

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