Kinesiology 4430F/G Lecture Notes - Lecture 10: Acetyl-Coa Carboxylase, Creatine Kinase, Neutrophil

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Sources of fatty acids in the systemic circulation. Beta receptors sensitivity to catecholamine"s is greatest in intraabdominal/visceral fat: fats that are available in visceral are easier mobilized therefore better chance to be oxidized/broken down. Greater subcutaneous adipose tissue deposit in whole body then in intraabdominal tissue: however, that tissue is much more receptive to catecholamine stimulation = breakdown is greater. Fa"s released from intraabdominal are taken up by the liver where they are repacked as vldl and ldl: these are the ones that have a greater effect on cvd because of ldl, Vldl: high vldl/ldl is associated with cardiovascular disease. Most of the ffa"s in blood are released from subcutaneous adipose tissue. Ldl, vldl contribute to plaque formation in arteries: ldl + vldl will accumulate the fat contents in atherosclerotic plaques, hdl will carry them away, why visceral fat is more dangerous then subcutaneous fat. Effect of testosterone (dht) on visceral fat in overiectamized mice.

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