Kinesiology 1070A/B Lecture Notes - Lecture 9: Psychotherapy, Vagus Nerve, Interpersonal Psychotherapy

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Study: initial severity and antidepressant benefits: a meta-analysis of data submitted to the food and drug administration (kirsch feb, 2008) Meta-analysis of anti-depressant medications have reported only modest benefits over placebo treatment and when unpublished trial data are included, the benefit falls below accepted criteria. Placebo- one trial was an inactive pill and one was active: psychological theory: belief in treatment or to a subjective feeling of improvement, critical factor: is our beliefs about what"s going to happen to us. Improvement was 9. 6 in the drug group, and 7. 8 in the placebo group (improvements on the depression scores) 0. 32, which falls below the 0. 5 standardized mean difference criterion. *- the drugs used to treat depression are effective, but for many, it"s not the active ingredient that"s making people feel better. Food and drug administration require companies to show that pill is more effective than a placebo in 2 clinical trials- even if many other drug trials failed.

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