Kinesiology 1080A/B Lecture Notes - Lecture 8: Dysmelia, Primary Motor Cortex, Thalidomide

• School: Western University
• Department: Kinesiology
• Course: Kinesiology 1080A/B
• Professor: Matthew Heath

Document Summary

Wed, jan. 30/19 lecture 8: dysmelia & phantom limb"s. Thalidomide and developmental dysmelia: dysmelia = incomplete limb, penfield"s idea of non-plastic neurons (they do not change) - he was wrong. Less expansive motor map for the hand, as opposed to someone who has fully developed limb. Seizure"s: neurons just briskly randomly fire all over the place: did the m1 motor map of people change because of people who had epilepsy. Study: kindling: chronically stimulate areas of the brain, harvested motor cortex of rat, unfolded spread on paper. Size of the motor map changed: kindled changes the organization of motor map in rats, penfield may be incorrect because he dealt with kindled humans (humans that were affected) Mirror neurons: phantom limb pain (neurons in the frontal cortex (mirror neurons, monkey see monkey do. Learning through observation - function of mirror neurons. Supplementary motor area - actions you decide: output to corticospinal pathway as well as m1 projections.