Kinesiology 3371A/B Lecture Notes - Lecture 4: Nun Study, Frontal Lobe, Cognitive Reserve

• School: Western University
• Department: Kinesiology
• Course: Kinesiology 3371A/B
• Professor: Joyla Furlano

Document Summary

There is a loss of brain tissue in alzheimer patients. There is also a build-up of plaque and tangles around the hippocampus, which can lead to the loss of memory and function. The alzheimer"s biomarker is actually present when a person is seen as cognitively healthy and then progresses from there. Memory decline is when we actually see the manifestation of the internal problem a point where it"s considered in an advanced stage. Education, leisure activities, occupational attainment and physical activity all prevent dementia. The higher your attainment in life, the more your brain is involved in those activities, and will lead to decreased chances of developing dementia. Sister mary got a high score on cognitive testing about the same as a 50 year old. Participants who underwent a walking intervention increased hippocampal volume. *vegf increases delivery of blood, nutrients, and overall brain function (angiogenesis) *igf and bdnf causes cell proliferation in the hippocampus, cortex, and cerebellum (neurogenesis)