Microbiology and Immunology 2500A/B Lecture Notes - Lecture 6: Adaptive Immune System, B-Cell Receptor, Cytotoxic T Cell
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17 Jan 2018
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Helper cells express cd4 on surface, cytotoxic have cd8 on surface. So proper term is b-lymphocyte and t-lymphocyte but we shorten to cell. The first time youre exposed to that pathogen, you develop primary immune response. Second exposure to that pathogen (h1n1 ex) is memory response. The first response, magnitude is smaller than memory. The amount of time differs too, 1-2 weeks for first response, with subsequent second exposure its 1-3 days. Response is adaptive, faster, more effective, and higher magnitude. First exposure could be natural or through vaccination. That pathogen must reach a certain threshold before adaptive immunity is triggered. Must have certain number of pathogen that have replicated/reach of number certain threshold before adaptive immunity is initiated. Whe(cid:374) b a(cid:374)d t (cid:272)ells (cid:272)ir(cid:272)ulati(cid:374)g = (cid:374)a (cid:448)e (cid:271)e(cid:272)ause ha(cid:448)e(cid:374)"t see(cid:374) pathoge(cid:374) What you get after is some b and t cells will remain as memory cells.
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