Microbiology and Immunology 2500A/B Lecture Notes - Lecture 3: Minimum Inhibitory Concentration, Lactam, Methicillin

• School: Western University
• Department: Microbiology and Immunology
• Course: Microbiology and Immunology 2500A/B
• Professor: Dr.Summers

Document Summary

Antimicrobial agents: disinfectants antimicrobial agents that are applied to inanimate objects (e. g. floors, tables, walls, etc. ) Antiseptics antimicrobial agents that are sufficiently nontoxic to be applied to living tissues (e. g. hand sanitizers) bleach: do(cid:374)"t use i(cid:374)ter(cid:374)all(cid:455) Antibiotics antimicrobial agents produced by bacteria and fungi that are exploited by humans (delivered topically and internally) Potentially can be toxic but can use internally. Alexander fleming (1881-1955) discovered penicillin in 1928 produced from penicillium colonies of staphylococci couldn"t grow around a contaminating mold. Nobel prize in physiology and medicine (1945) Antibiotics represent our most effective therapeutic against bacterial infections. The availability of antibiotics enables cancer chemotherapy, organ transplantation, all invasive surgeries, treatment of premature infants. 2 major problems: diminished interest from pharmaceutical companies to develop new antibiotics, b/c bacteria always develop resistance to antibiotics, so much work for nothing, bacterial resistance to antibiotics always happens. Treati(cid:374)g the(cid:373) (cid:449)ith a(cid:374)ti(cid:271)ioti(cid:272) a(cid:374)d the(cid:455) (cid:373)ight alread(cid:455) (cid:271)e resista(cid:374)t to it, (cid:455)ou do(cid:374)"t k(cid:374)o(cid:449)