Microbiology and Immunology 2500A/B Lecture : mycology and parasitology dr. colby class notes.docx
16 Jan 2014
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Diagnosis of malaria: serious malaria (deadly) will be associated with thrombocytopenia (low platelet, giemsa stained thick and thin blood films very good in experienced hands (stain count) worked very well, pcr is gold standard, but not widely available, rapid diagnostic tests. Strongyloidiasis diagnosis: eggs seldom found in feces, diagnosis requires finding the larval stages in feces or duodenal fluids (need 4 6 specimens, elisa and western blot are sensitive and specific (cross reacts with filaria and other helminthic infections) but do not distinguish between current and past infection. 2nd most common cause of blindness worldwide: larvae transmitted by black flies, adult worms develop in sc nodules (subcutaneous under the eye, microfilaria produced which migrate to the skin during daylight chronic skin problems, mf also migrate to cornea scarring produces corneal opacity. Clinical classification: yeasts, molds, dimorphic fungi grow as yeasts or molds depend on what they want to do at that moment, poisonous mushrooms (homobasidiomycetes) mycetism (mushroom poisoning)
