Microbiology and Immunology 2500A/B Lecture Notes - Lecture 2: Innate Immune System, Respiratory Tract, Reproductive System
13 Sep 2016
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Document Summary
Innate immunity is the first line of defense against a pathogen: constantly ready to destroy a pathogen, effective at stopping majority of pathogens at early stage. Properties of innate immunity: inherited from parents, born with innate immunity defenses, well-conserved through evolution. Share innate immunity with plants and vertebrates (vertebrates only have innate immunity) Innate immunity does not remember the pathogen: same immune response to aidentical patho. Innate immune defense: barriers, block pathogen entry into tissue, innate cells, rapidly eliminate pathogen that enter tissues. Innate immunity is more immediate than the adaptive response. Modes of pathogen entry into the body: gastrointestinal tract (ingestion) digestive, skin (wound, respiratory tract inhalation, reproductive tract. The easiest way of gaining entry is through the mouth and thus the most common is gastro and respiratory. All tracts are lined with epithelial cells which prevent pathogen entry. **which have a layer of keratin: waterproof and acts as a barrier.
