Microbiology and Immunology 3820A Lecture Notes - Lecture 1: Allergic Bronchopulmonary Aspergillosis, Aspergillus Fumigatus, Aspergillus Flavus

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Laboratories without biological safety cabinets must not work on any mold, except those believed to be dermatophytes. There are several identification criteria: growth rate in culture, presence of a yeast phase (is it dimorphic, colonial and microscopic morphology (most important, biochemical tests. Little barriers you see along the tubes are the septa, disk like. Invasive infections in severely immunocompromised patients, especially with prolonged neutropenia, mortality >50% Cause chronic sinusitis and aspergilloma (fungus ball in pre-existing pulmonary cavity) in immunocompetent patients) We evolved in this kind of environment so we are use to this unless your sinuses are clogged you can get sinusitis. Aspergillus hyphae in tissue: silver stain: Branching, y shape, 45* angle, all end up going the same way, repeated. 45* angle, branching out but all end up parallel this is the hallmark of aspergillus. Rapidly growing greenish colony which you often see on moldy bread. Famous mold that was fucking with alexander flemmings stephlococcal cultures in the.

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