Microbiology and Immunology 3820A Lecture Notes - Lecture 1: Campylobacter Jejuni, Campylobacter, Reactive Arthritis
Document Summary
Single polar flagellum which allows them to corkscrew their way through fluids faster than other bacteria. Microaerophilic and capnophilic, will not grown in air. Asaccharolytic don"t break down sugars and very fast. Presents in wild birds from the principal reservoirs for farm animals; in all surface water; consumption of uncooked meat/fish; in raw milk due to fecal contamination and occasionally to campylobacter mastitis. Transmitted through handling raw meat and cross-contamination of food. Can be grown from most poultry in stores. Air chilling reduces the number of bacteria. The most common cause of acute enteritis in developed countries. Two closely related species: c. jejuni and c. coli, > 100 serotypes. Acute enterocolitis has histological features indistinguishable from salmonella or shigella. Most strains produce a cholera-like enterotoxin and one or more cytotoxins explosive diarrhea. Incubation period is 1-7 days with a febrile prodrome. Most recover within a week but reactive arthritis develops in about 1% 1-2 weeks after onset.