Medical Biophysics 3503G Lecture 6: MEDICAL BIOPHYSICS LEC 4

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Western University
Medical Biophysics
Medical Biophysics 3503G
James Lacefield

MEDICAL BIOPHYSICS From last lecture Contrast detail analysis some advantages and disadvantages has direct link tto labbratory imae qualiteies we studied previously, contrast detail anlaysis allows to get intiuition, what type of fetures imporving reosuiton would help us detect better, what type of features imporivng SNR would help better weakness was it was limited to idealized test images, where you have circular feature you wanted to test aginst uniform background and in cancer imaging context, you’re more likely to counter something more complicated today we learn about tool that has ability to be applied to clinical images, but has disandavantage, that connection of this tool to basic image parrameters like resolution, and SNR is more abstract Reciever operating characteristic (ROC) this tool is applied in any situation where you want ti study ability to detect something tool is easiest to understand by describing its procedure, there’s a multistep procedure to use this tool, procedure is: Select one condition to detect or classify (ex. patient has tumour or not) focus on detecting To do experiment must image a large propulaion of indivieduals, including many individuals with/without disease (preselect individuals based on clinical criteria) Need a method to objectively or subjectively rate the image choose orginal parameter or criteria as basis for diagnosis Objective: size, contrast, etc. Subjective: N-pint scale indicating radiologists certainty about diagnosis (typically N = 5) ROC procedure Have 100 indivisuals, and rank on a 5 point scale Works by: No disease in patient, thye score 1 Pretty sure theres no cancer, score 2 Can’t diceide based on images, score 3 Pretty sure there is cancer based on images score
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