Medical Sciences 4930F/G Lecture Notes - Lecture 11: Neutrophil, Hepatocyte, Mallory Body
17 Apr 2015
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Document Summary
Investigate what else can happen to the body with a high fat diet. Risk factor 1: large waist circumference: associated with high degree of visceral fat, visceral fat. Deep within the body, cant pinch it. Adipose tissue acts as an active endocrine organ. Interleukin-6 (il-6: both of these are cytokines, not secreted from adipocytes but amount of adipose tissue affects secretion, decreased levels of. Interleukin-6 (il-6: a protein involved in inflammatory response, secreted by macrophages in stromal vascular fraction of adipose tissue, enters circulation and acts systemically, preferentially secreted from visceral adipose tissue. In order to get glucose into muscle cells need to have insulin to promote that uptake event. Insulin is small protein hormone, produced by pancreas. Insulin plays a role in regulating glucose concentration maintains glucose homeostasis. Effect of visceral fat: hyperinsulemia & more glucose in the blood.
