Microbiology and Immunology 2500A/B Lecture Notes - Respiratory Tract, Dental Caries, Lysozyme

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Infectious disease is the major cause of human mortality throughout history. Major increases in life expectancy from the early 1900s onward were mainly due to control of infectious diseases. Life expectancy is highest in north america, europe, and australia. Of the top 10 causes of death in high- income countries, only one is from infectious disease (lower respiratory infections). In low-income countries, lower respiratory infections, diarrhoeal diseases, hiv/aids, malaria, tb, and neonatal infections are all infectious diseases found in the top 10 causes of death. : there are multiple possible outcomes when a population is infected by a new infectious agent 1. The agent overwhelms and kills the host without being transmitted. The agent replicates within the host and is transmitted to a new host. New infections may produce a high death rate, but over the course of time, the host and agent adapt to one another and the disease normally becomes less virulent.

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