Microbiology and Immunology 2500A/B Lecture Notes - Caseous Necrosis, Gram Staining, Mycolic Acid

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Often called tb for tubercle bacilli: bovis. Causes tuberculosis in cows, rarely in humans. Humans can be infected by the consumption of unpasteurized milk leading to extrapulmonary tuberculosis: avium. Can cause tuberculosis-like illness in humans, particularly in aids patients: leprae. This lecture focuses on two diseases caused by the same genus, mycobacteria. Tuberculosis affects one-third of the world"s population at some point in their life. Out of these, one-tenth (of the one-third) will progress to active tuberculosis in their lifetime (actual sickness). Tb is contagious (spreads in the air) and if the active form is not treated, it will infect 10-15 people per year. In 2011, there were almost 9 million cases of tb with the highest rates per capita is in africa, but half of the new cases are in six asian countries (bangladesh, india, china, philippines, indonesia, pakistan). There are two types of drug resistant forms of tb:

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