Microbiology and Immunology 3300B Lecture Notes - B Cell, Natural Killer Cell, Lymphopoiesis

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Lecture 2 learning objectives: learn the characteristics of the cells which comprise our immune system, learn the origin and circulation of these cells, learn the morphology of these cells, learn the general function of these cells. Epithelium our barrier with the outside world. Epithelial surfaces are parts of the body that are exposed to the outside world this includes skin, lining of the lungs, lining of the intestinal tract, etc. Epithelial cells are specially evolved for the specific purpose of blocking out the outside world. Generic model of epithelium - not all epithelium share the same features: tight junctions and basement membrane are common to all epithelial cells. Tight junctions junctions between the epithelial cells, such a tight seal that not even water or salt can get through. Basement membrane - mesh work of very strong proteins, gives epithelium physical strength and provides enough flexibility to move.

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