Pathology 3240A Lecture 12: Congenital Diseases
15 Oct 2018
School
Department
Course
Professor
Document Summary
Come up through the vaginal canal and the cervix. Fetus inhales infected amniotic fluid into lungs, or acquires infection when passing through the birth canal during delivery. Leads to chorioamnionitis and funisitis (inflammation of the fetal membranes; chorion and amnion, and umbilical cord. Often leads to premature birth; inflammatory cells sit on the membranes and cause thinning and rupture of the amniotic sac. Acute chorioamnionitis: membranes are no longer transparent; they are opaque and coated with pus. If acquired early, may result in growth retardation, intellectual disability, cataracts, congenital cardiac anomalies, and bone defects. Cat ingests cyst from tissues of infected intermediate hosts and passes oocytes to feces. Can directly infect humans through contamination of human food or water, or from ingesting meat of intermediate hosts. Can cause miscarriage, stillbirth, and ophthalmologic and neurologic problems. Intrauterine hypoxia from nuchal cord (cord around the neck) Risk factors: prematurity (birth before 36 weeks of gestation)
