Pathology 3245B Lecture Notes - Lecture 12: Rickettsia, Paraneoplastic Syndrome, Blood Vessel
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See particularly obstructive lung (airway) diseases (emphysema, chronic bronchitis, asthma) p. 463-470; pulmonary infections (community-acquired and hospital acquired pneumonias, lung abscess, pneumonia in the. Immunocompromised host) p. 486-492, 500-504; and lung tumours p. 505-510. removal of waste products (co2) Airways, acini and secondary lobules, vasculature, lymphatics, pleura. Airways: include trachea, bronchi and bronchioles which include the terminal bronchioles and respiratory bronchioles. Acini : are units supplied by a single terminal bronchiole. It includes respiratory bronchioles and its distal alveolar ducts and alveolar sacs. Acinus is the basic unit of gas exchange. Alveolar sacs are lined by type 1 and type 2 pneumocytes. Type 2 cells are the progenitor cells for type 1 cells and produce surfactant. Tb = terminal bronciole (last order of airways with complete mucosal lining). Alveolar wall: gas transfer takes place across the alveolar-capillary membrane. The alveolar capillary membrane consists of: capillary endothelium, basement membrane and surrounding interstitial tissue, alveolar epithelium (type 1 and 2 pneumocytes).