Pathology 3245B Lecture Notes - Lecture 5: Endoscopy, Diverticulosis, Ulcerative Colitis

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M = f, age 40: causes, helicobacter pylori. Infection rate: < 40 yr = 20% 50 yr 50. Appendix: anatomy, size of finger, located [, acute appendicitis, very common; risk 1 in 10; peak 10-25 yr, cause, obstruction (fecalith) 50-80, cancer, pathogenesis, obstruction continued mucus secretion increased luminal pressure. Compressed veins ischemic injury; bacterial invasion: complications, perforation, periappendical abcess, peritonisis. Lower right quadrant, appendix, ascends, bend at liver (hepatic flexture), across upper abdomen (transverse colon), bend at spleen (splenic flexture), sigmoid = s shaped, Diverticulum is medical term for an outpouching of a hollow (or a fluid filled structure in the body. Its use implies that the structure is not normally present. Low fibre diet low volume stools bowel must contract more to move feces increased intraluminal pressure. Weak points in bowel muscle layer where blood vessels pass through. Cross section lining is pushed down through the thickend muscle to form outpouching. Diverticulitis allows bacteria through, into adjacent tissue, inflammation.

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