Pathology 3245B Lecture Notes - Lecture 7: Obstructive Lung Disease, Cystic Fibrosis, Lung Cancer
Document Summary
Objectives: structure and function of the lung, pneumonia, chronic obstructive lung disease, effects of smoking, lung cancer. Increased incidence as population ages (of respiratory disease) Increased incidence of lung cancer in women: women didn"t smoke as much and then became marketing target. Increased mortality rates in women due to lung cancer. Number of canadians affected by respiratory disease (order of most number of ppl affected): asthma, copd (often secondary to smoking, lung cancer, tb, cystic fibrosis. Right lung has 3 lobes; left lung has 2 lobes. Function: oxygenation of blood, removal of waste products (co2, requires: Bronchi (main, primary, secondary each of the lobes) Alveolar wall: aka alveolar septae, site of gas transfer, occurs across the alveolar capillary membrane. The alveolar capillary membrane (site of gas exchange: type 1 and 2 pneumocyte, interstitial tissue, endothelial cells. Two systems of vessels (blood supply: pulmonary, bronchial. Interfere with either of the two processes (ventilation and perfusion) can lead to: