Pathology 3500 Lecture Notes - Lecture 28: Myxedema, Oligospermia, Endemic Goitre

• School: Western University
• Department: Pathology
• Course: Pathology 3500
• Professor: shepherd

Document Summary

Posterior pituitary pathology is usually due to too much adh. Can be a deficiency of adh as well usually from a lesion - end result is impaired water absorption and result is polyuria which is too much urine and then you get dehydrated. Summary: anterior pituitary, hyper function: adenomas (prl, gh, micro or macro-adenomas may be clinically silent or null cell adenomas, hypofunction- most common cause - tumors. Hypothalamus causes anterior pituitary gland to release tsh which goes to thyroids and causes t4 and. T3 to release t4 is turned into t3 and goes into blood stream. Causes of hyperthyroidism: primary cause, graves disease, hyper functioning multinodular goitre, hyper functioning thyroid adenoma. Laboratory diagnosis of hyperthyroidism: most cases have tsh levels decrease and t4 and t3 are increased (free t4 levels are increased, radioactive iodine scans may be useful in determining etiology.