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Class Notes for shepherd

Introduction To Human Pathology

Pathology 3500 Lecture 27: Lecture 27
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Lecture 27 The endocrine system Has a lot to do with hormones and hormones are like signals that signal one cell type to another The endocrine system refers to the group of glands that produce hormones functioning to regu...

Pathology
Pathology 3500
shepherd
Pathology 3500 Lecture Notes - Lecture 28: Myxedema, Oligospermia, Endemic Goitre
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Lecture 28 - Endocrine 2 Posterior pituitary pathology is usually due to too much ADH Can be a deficiency of ADH as well usually from a lesion - end result is impaired water absorption and result is polyuria which is too...

Pathology
Pathology 3500
shepherd
Pathology 3500 Lecture 32: Lecture 32
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Lecture 32 Bladder Bladder Gross Anatomy Urinary Reflux

Pathology
Pathology 3500
shepherd
Pathology 3500 Lecture 30: Lecture 30
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Lecture 30 Kidney Kidney and Urinary Tract Dr. C. Armstrong Kidney Functions Elimination of toxins, drugs, metabolic waste Maintain electrolytes, water balance, blood pH Regulate blood pressure (renin) Regulate Vitamin D ...

Pathology
Pathology 3500
shepherd
Pathology 3500 Lecture Notes - Lecture 31: Sepsis, Cardiac Output, Urinary Retention
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Lecture 31 Kidney cont. It Can Get Complicated - wont put emphasis on this, dont even think we need this list Minimal change disease Focal segmental glomerulosclerosis Membranous glomerulopathy Dia...

Pathology
Pathology 3500
shepherd
Pathology 3500 Lecture 26: Lecture 26
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Lecture 26 Pediatric Pathology Pretty much is everything is in the lecture notes Also dont need to read text Perinatal infections Hydropic fetus: baby swollen with water o End stage of many diseases in utero Organism that...

Pathology
Pathology 3500
shepherd
Pathology 3500 Lecture Notes - Lecture 29: Glycosuria, Osmoreceptor, Hepatocyte
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Lecture 29 Endocrine 3 Congenital Adrenal Hyperplasia Results from a number of autosomal recessive enzymatic defects in the biosynthesis of cortisol from cholesterol o Deficiency of 21 hydroxylase (90 of cases), this conv...

Pathology
Pathology 3500
shepherd
Pathology 3500 Lecture Notes - Lecture 20: Obesity Hypoventilation Syndrome, Xerophthalmia, Amenorrhoea
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Lecture 20 Metabolic and nutritional disorders II Nutrition: what is a healthy diet A heathy diet provides o Enough energy for the bodys metabolic needs (From CHO, fats, proteins) o Essential and nonessential amino and fat...

Pathology
Pathology 3500
shepherd
Pathology 3500 Lecture Notes - Lecture 24: Cytogenetics, Scrapie, Comparative Genomic Hybridization
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Lecture 24 Molecular genetics cont. NonMendelian Inheritance Trinucleotidetriplet repeat expansion: Huntingtons disease, Kennedys disease, Fragile X syndrome,... o Carry a trinucleotide for a disease, the expansion can co...

Pathology
Pathology 3500
shepherd
Pathology 3500 Lecture Notes - Lecture 25: Haplotype, Chromosome, Microsatellite
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Lecture 25 Molecular genetics cont. Detection of Mutations can sequence genomes very easily now Testing methodstrategy must fit the mutation NOW: DNAbased (historically mutations were detected by abnormal gene products) ...

Pathology
Pathology 3500
shepherd
Pathology 3500 Lecture Notes - Lecture 23: Haploinsufficiency, Autosome, Monosomy
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Lecture 23 - Molecular genetics Objectives Central dogma of molecular biology Types of mutations Mendelian vs. non-Mendelian inheritance Basic concept of experimental/diagnostic tools in genetics ...

Pathology
Pathology 3500
shepherd
Pathology 3500 Lecture Notes - Lecture 21: Karyotype, Nuclear Weapon, Cell Migration
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Lecture 21 Congenital and Genetic Diseases Congenital disease Presence at birth May be secondary to a genetic etiology but also maybe not Genetic disease Determined by genes This can be present at any time What is a congen...

Pathology
Pathology 3500
shepherd
Pathology 3500 Lecture Notes - Lecture 22: Teratology, Malabsorption, Low-Density Lipoprotein
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Lecture 22 Congenital and Genetic Diseases cont. Numeric abnormities Autosomes o Ex. Down syndrome (trisomy 21) Sex chromosomes o Turner syndrome (XO) o Klinefelter syndrome (XXY) Down syndrome (trisomy 21) o Most common c...

Pathology
Pathology 3500
shepherd
Pathology 3500 Lecture Notes - Lecture 11: Chemokine, Calorie, Chronic Myelogenous Leukemia
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Lecture 11 Biology of tumor growth Monday, October 23, 2017 8:14 AM Biology of tumor growth Transformation (normal to tumor cell) Growth of tumor cells, angiogenesis, tumor progression and heterogeneity Local invasion Met...

Pathology
Pathology 3500
shepherd
Pathology 3500 Lecture Notes - Lecture 15: Kidney Disease, Colloid, Endothelium
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Lecture 15 Disturbances of blood flow and body fluids Monday, November 6, 2017 8:16 AM Vascular hemodynamics abnormalities Blood flow normal fluid homeostasis o Edema o Hyperemia o Hemorrhage Maitance of blood as a liquid ...

Pathology
Pathology 3500
shepherd

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