Class Notes (836,326)
Canada (509,734)
Pharmacology (354)
Lecture 9

Lecture 9 Ethics.pdf

1 Page
84 Views
Unlock Document

Department
Pharmacology
Course
Pharmacology 4350A/B
Professor
Rommel Tirona
Semester
Winter

Description
Lecture9 Ethics April-22-12 9:02AM BelmontReport-GuidingprinciplesforHumanResearch 1. RightforAutonomy 2. Beneficence 3. Justice(equalchance,unbias) - ClinicalEquipoise -HonestGenuineuncertaintyofthedruginquestionandcomparatordruggoinginto clinicaltrial - PHIPA-personalhealthinformationprotectionact(privacydisclosure) - HSREB- healthscienceresearchethicsboard 1. Validscientificdesign 2. Researchstudyquestionhasvalue 3. Studyconductedhonestly 4. Reportedaccuratelyandpromptly 5. Assessmentsofbenefitsvsrisk 6. Informedconsent  Clarifyrisksanddiscomfort+identifypotential benefits+explainalternative treatments+ whathappensduringinjury+contacts+ voluntaryparticipationandmayleave anytime  Specificconsent+Tieredconsent+general permission+presumedconsent Vulnerablegroups 1. Children - History ○ EdwardJenner-1790, injected2boyswithcowpoxto seeiftheywerevaccinatedagainst smallpox ○ Mentallychallengedchildreninstitutionashepatitisresearch - Unabletogiveinformedconsent(proxyconsent) ○ Childwithintellectualage>7 - Risk ○ Mustbeminimalrisk(notgreaterthaneverydayrisk)+greaterbenefitscompensatesforincrease risk 2. Women - Therapeuticresearch -researchinvolvingsubjectswithaspecificdisorderandthestudymayprovide - Excludedfromtrialsuntil90s ○ Moreunethicaltogivetreatmentwithoutevidence+men/womenarediff benefits
More Less

Related notes for Pharmacology 4350A/B

Log In


OR

Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


OR

By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.


Submit