Pharmacology 3620 Lecture Notes - Lecture 21: Anxiolytic, Dsm-5, Acetylcholine Receptor

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The treatment of addiction has two phases: 1. Where the individual ceases usage of a drug whether gradually or abruptly. Once committed, it is a fairly straightforward process. Palliative care can be provided to reduce withdrawal symptoms of those who were severely addicted. For example, alcohol withdrawal can cause seizures, so benzodiazepines would be given: 2. Once established, addiction can be a life-long/chronic condition because of biochemical and epigenetic changes. May require months to years of therapy (pharmacological and behavioral- very rare to only have one therapy without the other) 3 different endpoints of addiction any or all of these 3 endpoints = addiction. Dependence: the need for repeated administration of the drug to prevent an adverse effect (e. g. sweating, tremors). I. e. if you stop taking the drug, you will get an adverse effect. Withdrawal: manifestation of the adaptive effects that have occurred due to repeated drug use and o(cid:374)e"s dependence on it for normal function.

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