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Lecture

Consciousness, Evoked potential, EEG & sleep

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Department
Physiology
Course
Physiology 3120
Professor
Tom Stavraky
Semester
Fall

Description
Human Physiology Monday, November 23, 2009 “Neuro XIV” Consciousness, Evoked Potential, EEG, and Sleep • Two components of consciousness  Content of consciousness; cerebral cortex functions (memory, perception, etc.)  Level of consciousness; reticular system in the brainstem • Evoked potentials  Primary & secondary (only worry about primary)  Only observed in the leg area of the somatosensory cortex; activation of different populations of neurons will produce different patterns  Change in voltage; results from summation of extracellular currents associated with post- synaptic potentials; not local currents associated with APs (see figure)  Current from DCML axons doesn’t contribute to evoked potential  Depolarization of cortical neurons occurs in the cell body; current flows out to the dendrite and out into the extracellular space (most of it goes back down to the nerve, but some is recorded by the electrodes on the surface of the skull)  APs originating at axon hillock contribute nothing to the evoked potential  Used to (I) determine integrity of reticular pathway, and (II) elucidate somatotopic organization of cortex • Electroencephalogram (EEG)  Neurons fluctuating between EPSPs and IPSPs at about 10 Hz during one form of sleep  Interneurons in the thalamus inhibit themselves,
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