Physiology 3120 Lecture Notes - Gastrin, Pylorus, G Cell

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Stomach secretion: functionally different regions (look the same, but different functions) Proximal part (2/3 of total volume) = oxyntic gland area. The cell that produces hcl is called the oxyntic/parietal cell: diffuse scattering of cells throughout mucosa (i. e. there isn"t a distinct gland) Distal part (1/3 of total volume) = pyloric gland area. Small exocrine function, but its major function is endocrine; the hormone released is gastrin (eventually released into vasculature) Gastrin circulates in the blood and gets to the oxyntic cells; has a stimulatory effect on. The cell that releases gastrin is called the g cell; also randomly distributed throughout. Hcl secretion: regulation of acid secretion pyloric gland area. Typically, acid secretion is broken down into 3 phases, divided based on where the stimulation is at any point in time; food is the primary stimulation for any area of the gi tract. Not a sequential process; may have all 3 phases activated simultaneously: cephalic phase.

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