Class Notes (835,513)
Canada (509,212)
Physiology (1,062)
Tom Stavraky (262)

Gastric secretion

2 Pages
Unlock Document

Physiology 3120
Tom Stavraky

Human Physiology Wednesday, March 24, 2010 “Gastro III” Gastric Acid Secretion 2. Gastric phase  Occurs after food has entered the stomach and sits there  Perceptive input has been removed  2 ways to modulate acid secretion during this phase a. Physical presence of the food mass, which causes mechanical stretching of the stomach wall o Distension of stomach increases acid secretion; put balloon in stomach and inflate it  increases acid i. Primarily due to nervous reflexes; activate stretch receptors within muscle and mucosa that can activate a vagal afferent-efferent reflex pathway; this releases ACh and gastrin; called the vago-vagal reflex ii. Within the wall of the stomach, have enteric nervous system (cholinergic); it is a plexus (connects around the entire gut) that receives information from stretch receptors; enteric nerves synapse on the oxyntic cells, and receives information from stretch receptors o The enteric-mediated responses are inter-regional as well as intra-regional; can stimulate in oxyntic area and get responses in oxyntic and pyloric gland area b. Chemical caused by some of the foodstuffs o Most potent stimulus is protein or even small peptides; seems that the cells respond directly to these compounds to activate secretion of their compounds 3. Intestinal phase
More Less

Related notes for Physiology 3120

Log In


Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.