Physiology 3140A Lecture Notes - Lecture 6: Galactose, Membrane Transport Protein, Main Source
10 Dec 2013
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Document Summary
Blood is filtered in the kidney and it is filtered in the filtering apparatus of the nephrons. Anything filtered into the nephrons is called the filtrate. The passage of the filtrate travels down the tubule of the nephron. The important parts of the tubule are the proximal tubule, ascending limb of the loop of henle, and the collecting duct. The tube is not like a garden hose or not just matrix; it is cellular, specifically epithelial. If you take a section of the tubule, the part of the section that has the villi is on the inside of the tubule and the cells are facing the body of the kidney. Components of the filtrate can continue to pass or absorbed/ reabsorbed through the cells. In case of tight junctions, it is movement of molecules in between cells, passed the tight junctions. If the occluding junctions are tight, then there would be no paracellular motion and vice versa.
