Physiology 1021 Lecture Notes - Lecture 16: Paracellular Transport, Aquaporin, Collecting Duct System

• School: Western University
• Department: Physiology
• Course: Physiology 1021
• Professor: John Ciriello

Document Summary

Aquaporin i one faces lumen, no hormonal. Focus: ions and the multi-porter where there are 4 ions each time. Aquaporin ii luminal membrane of the collecting duct cells. Aquaporin iii or aquaporin iv is the basolateral membrane water channel, due to different genes. Chart *5 segments and the order compared to what they reabsorbed (ions, water) then whether or not if there is hormonal regulation. 5 segments and what the channels or transporters each section contains, which membrane they are on and whether or not the sections are hormonally regulated excrete excess salt or secrete. Hormones, antidiuretic hormone, angiotensin ii, aldosterone, anp. * both stimulate the release of antidiuretic hormone released from posterior pituitary increases (just like hyper tonic) to brain. Mechanism of adh adh synapses increasing the number of aquaporin channels in the collecting duct. If you have low sodium in the body result of cutting protein several times: starts off as angiotensinogen (liver)