Physiology 1021 Lecture Notes - Lecture 9: Corpus Luteum, Follicular Phase, Theca

• School: Western University
• Department: Physiology
• Course: Physiology 1021
• Professor: John Ciriello

Document Summary

Ovulation occurs at approximately day 14, although exact timing is dictated by lh surge. This surge is due to positive feedback by estrogen on the anterior pituitary, which is triggered by high estrogen levels. Secondary oocyte is released from ovary by a rupture in the ovarian wall while the majority of the granulosa and theca cells remain within the ovary. Secondary oocyte moves down the fallopian tube for possible fertilization, however, other ovarian events continue that involve remaining granulosa and theca cells. These cells develop into a corpus luteum, initiating luteal phase: early to mid follicular phase: Estrogen levels start to rise because it can stimulate the cells that made estrogen or near by cells so there"s positive feedback as estrogen goes up you get more granulosa cells, therefore more estrogen: late follicular phase: Don"t know why it switches to positive feedback. When we reach certain number of estrogen, its positive feedback.