Physiology 1021 Lecture Notes - Lecture 10: Zona Pellucida, Acrosome Reaction, Granulosa Cell

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In an ejaculation, there are over 100 million sperm. These sperm must be able to swim in order to reach the ovum in the fallopian tube. Also must have ability to bind and fuse with ovum and eventually penetrate the zona pellucida for fertilization to occur. Head: contains nucleus (dna), 23 chromosomes, contain enzymes that can act to degrade parts of oocyte. Occurs in how sperm swim and around sperm which more able to bind female reproductive tract must happen before sperm can fertilize an ovum. Alters: sperm motility (increases), sperm plasma membrane (enhanced capacity to bind to oocyte) Describe the route sperm must travel for fertilization to occur. Ovulation- secondary oocyte is released and swept by fimbrea into tube and swept down by cilia. Introduction of sperm into reproductive tract swims up cervix into uterus, into fallopian tubes. 200 million sperm, some die, some get destroyed, only 100 make it to the egg and only 1 fertilizes it.

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