Physiology 2130 Lecture Notes - Lecture 1: Posterior Pituitary, Paraventricular Nucleus Of Hypothalamus, Leptin Receptor

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*saiety means full anterior hypothalamus controls parasympatheic acivaion posterior hypothalamus controls sympatheic acivaion. Oxytocin: hormones travel down hypothalamic posterior pituitary stalk and are released directly into the posterior pituitary capillary bed. Neural-humoral relex (neural-endocrine relex) neural pathway relexes endocrine pathway: humoral means body luids. Mechanical simulaion at the nipple triggers neural signal: signals hypothalamus to synthesize oxytocin posterior pituitary simulated to release oxytocin stored in nerve terminals into circulaion oxytocin simulates milk secreion and producion at the breast. Note: oxytocin operates through a posiive feedback of control (rare) oxytocin neurons increase their discharge more to each simulus: more eicient release of hormone each simulus is addiive. *this neuro circuit is sexually dimorphic only acive ater delivering baby otherwise circuit is not operaional neural plasicity; connecions can be made and taken away. Acivaion of vasopressin neurons vasopressin (adh) operates through a negaive feedback system unlike oxytocin which operates through a posiive feedback system.

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