Physiology 3120 Lecture Notes - Lecture 12: Motor Action F.C., Inferior Olivary Nucleus, Thalamus

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10% volume & contains more than half the neurons in brain. 5 cell types cortex (connected same way in all regions: 2 excitatory, 3 are inhibitory. Information goes up the cortex with a branch going to deep nuclei (excitatory) Information continues up and synapses with granule cell (excitatory) Granule cells sends parallel fibres to purkinje cells (excitatory/inhibitory: purkinje junction is modifiable! Purkinje cell synapses with deep nuclei (inhibitory: diverse input - no consciousness, p cell only output, always inhibitory, medial/lateral, primates lateral increase, cognitive. Functions of lateral are different from medial side (in terms of histological connections that occur) Lesions in lateral or medial side is due to 2 arteries in the region of cerebellar nuclei. Stroke in one or the other causes problems on lateral or medial side. Large repertoire of movements in humans and may largely be controlled by pyramidal tract (skill and refinement)

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