Physiology 3120 Lecture Notes - Lecture 13: Heritability, Dyskinesia, Spasticity

• School: Western University
• Department: Physiology
• Course: Physiology 3120
• Professor: Tom Stavraky

Document Summary

3 area of the cerebral cortex that can influence the motor cortex: parietal cortex body image, pre-motor cortex instructing motor cortex, supplementary motor area receives input from basal ganglia. Basal ganglia is one of the nucleus within the hemisphere of the brain. D1 (dopamine) (dopamine) (gaba) (gaba) (ach is transmitter for interneurons) (ach is transmitter for interneurons) (gaba) (gaba) Neurologists: balance ach/dopamine, c/p external globus pallidus subthalamic nucleus internal globus, direct/indirect pathway, c/p internal globus pallidus direct pathway. Pallidus indirect pathway: typically have equal flow through these 2 pathway, gaba inhibitory transmitter, one major output to thalamus. Cognitive: planning, working memory, attention [absent minded, reasoning ability, dementia, tourettes, ocd] When a movement is to be made, basal ganglia selects neural programs by releasing them from inhibition (takes off the brakes) There"s an imbalance bw dopamine and acetylcholine dopamine decreases and acetylcholine goes up.