Physiology 3120 Lecture Notes - Lecture 6: Acute Respiratory Distress Syndrome, Obstructive Lung Disease, Pulmonary Function Testing
Document Summary
Restrictive vs obstructive lung disease: asthma. Blood gas barrier is very thing and has a very large surface area. Increased pco2 sends signal to cause vasoconstriction (diverts blood to areas where fresh gas is coming in) Lung tries to limit airflow where there is no blood flow. Physical environment of the lung: negative intrapleural pressure. Air in intrapleural space (air leakage into the intrapleural space) Small spontaneous pneumothorax may resolve without treatment. Treatment may include insertion of a chest tube. Occurs more often in women, people who are tall and skinny, and smokers. Result: lung is continuously exposed to inhaled particles, bacteria and other pollutants. Depending on the size, particles may deposit in larger airways (larger particles) or in the smaller airways and even in alveoli. Occurs according to two basic mechanisms: mucus (are then swept up by epithelial cells lining the airways and can be expelled out or swallowed, alveolar macrophages.