Physiology 3120 Lecture Notes - Autonomic Nervous System, Adrenergic Agonist, Purinergic Receptor

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2 classic symptoms counter anaphylactic shock: sympathetic/parasympathetic tone , enteric nervous system causes vasodilation. Decrease in blood pressure (can lead to breathing) These effects are controlled by beta receptors, which are more responsive to epi, so give epi to. Basal rate of neuron discharge (about 1 ap per few seconds; can reach about 20 aps/sec); much lower tone than those of the somatic ns. Allows a single system to increase & decrease activity of stimulated organ. For arterioles, increased discharge causes vasoconstriction, and decreased discharge. Isoproterenol = manufactured adrenergic agonist: goal of drug companies is to manufacture specific agonists/antagonists to specific receptors and receptor subtypes relaxation) Alpha-adrenergic receptors can be excitatory (vasodilation) or inhibitory (iris dilation, intestinal. Beta-adrenergic receptors can be excitatory (heart acceleration) or inhibitory (bronchodilatation: adrenal medulla secretes nor/epinephrine (80% epi; has a greater effect on heart because heart has beta receptors, which respond to epinephrine much more strongly than norepi)

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