Physiology 3120 Lecture Notes - Antral Follicle, Corpus Luteum, Androgen-Binding Protein
20 Nov 2012
School
Department
Course
Professor
Document Summary
80% of testis mass is the seminiferous tubules. Adjacent sertoli cells create blood-testis barrier via tight junctions. Spermatogonia possess 2n (are diploid) number of chromosomes. Speratocytes cells in the process of becoming sperm. Cell acquires a vesicle of enzymes called the acrosome. Fluid is added by the seminal vesicles, prostate gland and cowper"s gland. Factors which affect spermatogenesis requires temperatures lower than 34 degrees. Fsh is required for the initial waves of spermatogenesis and when is must be re-initiated. Sertoli cells have fsh receptors, binding initiates the production and secretion of androgen binding protein which functions to maintain high local concentrations of testosterone. Entire process takes about 64 days sperm reside in the epididymis for 2 weeks. While testicular sperm used glucose as an energy substrate and for conversion to a. a"s and lipids, capacity to do this is lost in the epididymis. 17-b-hydroxy steroid dehydrogenase cholesterol is the principle precursor for all steroid hormones.
