Psychology 2020A/B Lecture Notes - Lecture 11: Khat, Vin Mariani, Nasal Congestion
Document Summary
It"s often diverted into the illegal production of methamphetamine. There is evidence of physical dependence but not psychological dependence. It became illegal in canada in 1997, but it"s still legal in the united kingdom: methcathinone is a slightly modified version of the active ingredient in khat and was first synthesized to treat depression. Chronic use leads to destruction of dopamineric neurons. It releases dopamine in the vta thereby producing an euphoric effect. Coca and cocaine: the use of the coca leaf has been used as far back as 1000bc and the use continued throughout a variety of cultures. It was realized that native individuals could work longer and have less need for food if they chewed coca, which results in a low dose effect. Results in mild mental and physical stimulation: then there was the isolation of cocaine as the active alkaloid in the coca leaf in 1859 by albert niemann.