Psychology 2660A/B Lecture Notes - Partial Agonist, Intramuscular Injection, Drug Tolerance

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Chemical name : describe type of molecule and location of chemical group. The generic name or non-proprietary name: commonly used and can be used by any company marketing the drug. Trade name or proprietary name: given and only used by the same company. Administration => absorption => distribution (via circulatory system) => x => metabolism (metabolized to an inactive form) => elimination. Pharmacodynamics: x = drug reaches the sa and interact with the rc. Oral: must pass from stomach or small intestine then bloodstream: stomach: highly acid so might destroy drugs, exit to small intestine (more alkaline environment: diffusion (high cm to low cm) into. If alkaline drugs: they are ionized and cannot pass out in bloodstream so bloodstream: liver: might metabolized a part of the drug: Cytochrome p-450 in endoplasmic reticulum of liver cells (enzyme). This enzyme is inducible, is activity might be potentiated. Snorting: albert hoffman found lsd (first acid trip)

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