Psychology 3316F/G Lecture Notes - Lecture 7: Virtual Reality, Escitalopram, Etiology
Document Summary
Psychology 3316 lecture 7 - psychobiology of ptsd and it"s treatment. Intermediate markers between top-level (human) symptoms and bottom-level genetic contributions. Between genes and behaviour you have a middle ground. Important to focus simultaneously on at least two separable elements of animal models. Heritability estimates for most psychiatric disorders approximate > or = 50% and certain disorders are highly heritable (80% in bpd) Most clearly obtained by comparing co-prevalence between mz and dz twins on assumption of shared environment . Common in general population and have small effects in predicting diagnosis. Any significant genes usually have a small effect. Rare in general population and may have large effect in predicting diagnosis. Really no such thing as variants of large effect, they would have been found by now. Argument that some mental illnesses may be uniquely human. Would not learn anything from animal model (ex. schizophrenia) Fairly decent animal models for ptsd (fear responses, aggression, withdrawal)