BI111 Lecture Notes - Lecture 14: Amphiphile, Hydrophile, Transmembrane Domain
Document Summary
Transmembrane domain: chains that stretch across the membrane (single or multiple) Typically, there are 20 amino acids to get across. With the ones of the either less or more, they can have shorter phospholipid making it more or longer depending on thickness and size. Stated isolated cells (cultured from other cells) from mice and human. Critical part labelled the cells with fluorescent dyes. Mixed them together in a certain condition. Formed a large hybrid cell (half red and half green) 40 min 37c found- no longer red or green but an even distribution of both colours. More dense the phoslip. b tight pack= less fluid. Effect of unsaturated fatty acids on packing of membrane lipids (composition) Saturated: single bonds, denser, less space, straight chains, less fluid, tighter packing. Unstaturated: double bonds, less dense, more space (in the mono un. s. there is the kink), fluid becomes higher. Viscous: not very fluid (think of butter: cold hard- warm fluid)
