BI110 Lecture Notes - Glycolysis, Superoxide Dismutase, Pyruvic Acid

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17 Sep 2013
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It cannot get across the inner membrane with the protein. Less then ten years ago they found this protein. Catalyzed by pyruvate dehydrogenase: removes the carboxyl group which yields carbon dioxide. Electrons removed in oxidations: accepted by nad+ or fad. Each acetyl group oxidized produces: 2 co2, 1 atp, 3 nadh, 1 fadh2. In this process, coa is available to go back and participate in pyruvate oxidation and participate in the cycle again, it is not recycled as part of the citric acid cycle, it is the carbon backbone. It takes the 2 carbons from acetyl-coa and attaches them to oxaloacetate. One turn of the citric acid cycle: 1 acetyl-coa + 3 nad+ + 1 fad + 1 adp + 1 pi + 2 h2o 2 co2 + 3 nadh + 1 fadh2 + 1 atp + 3 h+ + 1 coa. Electrons passed from nadh and fadh2 to o2.

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