BI110 Lecture Notes - Lecture 11: Exergonic Reaction, Catabolism, Cellular Respiration

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24 Oct 2013
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Entropy decreases as substance changes from liquid into solid. Entropy of system + surroundings (universe) always increases. Rate of forward and reverse reactions are equal when reaction reaches equilibrium. Exergonic reactions have a -ve deltag value (spontaneous reaction) Cellular respiration is example of catabolic pathway. Atp slightly unstable due to -vely charged phosphate that tend to repel each other. Atp is an unstable and high energy molecule. Anabolic and metabolic pathways use atp; all organisms use atp. Atp and energy coupling: hydrolysis of atp is an exergonic reaction that can be coupled to make otherwise endergonic reactions proceed spontaneously. Energy released from exergonic reaction is used to drive endergonic reaction: coupling reactions require enzymes. 10 million molecules of atp hydrolyzed per second in a cell. A spontaneous reaction does not necessarily occur quickly. Enzymes are special group of proteins that can alter speed of reaction. Initial input of energy to start a reaction; even if it"s spontaneous.

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