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Lecture

BI110 4th November, 2013.doc

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Department
Biology
Course
BI110
Professor
Matthew Smith
Semester
Fall

Description
4 November, 2013  Glycolysis Overview. - Universal, ancient pathway. - Doesn’t require O2 - In cytosol - Glucose (6C) oxidized into 2 molecules of pyruvate (3C each) - Electrons removed are delivered to NAD+ producing NADH - Each glucose molecule oxidized produces • 2 net ATP • 2NADH • 2 Pyruvate EXPECT KNOW!!! Phosphofructokinase ATP produced during glycolysis is produced by kinase enzyme. NAD+ is reduced by dehydrogenase enzyme 2 molecules of pyruvate still consume 75% of ATP  ATP synthesis by substrate level phosphorylation - ATP molecule produced in glycolysis result from substrate level phosphorylation. - Enzyme catalysed reaction - transfers phosphate group Clicker 1, Which of the following processes occurs during glycolysis? D. ATP production through substrate level phosphorylation.  Reactions of pyruvate Oxidation - MPC- mitochondrial pyruvate carrier. - ^ active transport + - pyruvate + CoA +NAD+  acetyl-CoA + NADH +H +CO 2 - pyruvate must be transported across 2 membranes - non selective porins a
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